Lot numbers can be found on the outside label of a product:
Please log in for operation!
*For research and further manufacturing use only, not for direct human use.
Structure of 1150560-54-5
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
This fluorinated pyrimidinedione integrates a trifluoromethyl group and iodine substituent, enabling direct functionalization in late-stage diversification. The 2-fluoro-6-(trifluoromethyl)benzyl moiety enhances metabolic stability and lipophilicity, while the iodo handle facilitates cross-coupling reactions under standard conditions.
1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-iodo-6-methylpyrimidine-2,4(1H,3H)-dione serves as a versatile building block for the synthesis of substituted pyrimidinediones, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling. The iodide group facilitates reliable coupling with diverse nucleophiles, while the trifluoromethyl and fluorinated aromatic moieties provide enhanced metabolic stability and lipophilicity—key attributes in medicinal chemistry. Bench-stable and compatible with standard purification methods, it functions effectively in multistep synthetic sequences targeting bioactive heterocycles.
|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P280-P302+P352
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Lot numbers can be found on the outside label of a product: