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Structure of 1150561-70-8
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3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile delivers a boronate ester functionality paired with a nitrile group on a picolinate scaffold. This bench-stable reagent enables direct coupling in Suzuki-Miyaura reactions, integrating efficiently into complex molecular architectures under mild conditions.
3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The picolinonitrile core provides a rigid, electron-deficient heterocyclic scaffold with orthogonal functionality, enabling efficient diversification in medicinal chemistry and materials synthesis. The stable boronate ester group facilitates mild coupling conditions, excellent functional group tolerance, and straightforward purification, making it ideal for modular library construction and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: