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Structure of 741709-63-7
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile features a boronate ester group paired with a nitrile-substituted pyridine ring, enabling efficient Suzuki-Miyaura coupling under mild conditions. The tetramethylcyclohexadienyl moiety enhances stability and moisture tolerance, while the electron-deficient pyridine facilitates selective reaction with aryl halides. This structure supports modular synthesis of functionalized heteroaromatics in medicinal chemistry and materials science workflows.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile serves as a versatile boronate building block for palladium-catalyzed cross-coupling reactions. The picolinonitrile moiety provides a readily accessible handle for further functionalization, while the tetramethylboronate group ensures excellent stability, mild handling requirements, and compatibility with diverse reaction conditions. This compound facilitates efficient synthesis of substituted pyridine derivatives relevant to medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: