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CS-W001157 4
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(1-Aminocyclopropyl)methanol hydrochloride

  • CAS No. 115652-52-3

  • Cat. No. CS-D0148
  • Molecule weight123.58
  • Purity≥97%
  • MDL No.MFCD09834330

*For research and further manufacturing use only, not for direct human use.

(1-Aminocyclopropyl)methanol hydrochloride|CS-D0148

Structure of 115652-52-3

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General Information

  • CAS No. 115652-52-3
  • Cat. No. CS-D0148
  • Purity ≥97%
  • MDL No. MFCD09834330
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO
  • Molecular Weight 123.58
  • Synonym(s) 1-Amino-cyclopropanemethanol HCl
  • SMILES OCC1(N)CC1.[H]Cl

Description

(1-Aminocyclopropyl)methanol hydrochloride is a bench-stable, moisture-tolerant amino alcohol derivative featuring a strained cyclopropyl ring. This compact scaffold integrates a primary amine and hydroxymethyl group in close proximity, enabling efficient coupling reactions and serving as a key building block in bioactive molecule synthesis.

Application

(1-Aminocyclopropyl)methanol hydrochloride serves as a stable, bench-ready building block for the synthesis of cyclopropyl-containing bioactive molecules. Its amino-alcohol functionality enables straightforward derivatization via reductive amination, amide coupling, or cyclization reactions. The hydrochloride salt enhances solubility and handling, facilitating integration into multi-step synthetic sequences for medicinal chemistry and process development.

Synthesis

  • Route1

    References

    • Journal of Medicinal Chemistry, , vol. 31, # 10 p. 2004 - 2008

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P264-P280-P305+P351+P338-P337+P313

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   -0.1082
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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