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Structure of 1159512-38-5
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2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine is a fluorinated heterocyclic building block featuring orthogonal halogen handles for selective cross-coupling. The trifluoromethyl group imparts enhanced lipophilicity and metabolic stability, while the electron-deficient pyridine core enables efficient Pd-catalyzed transformations. This compound serves as a key intermediate in medicinal chemistry and agrochemical synthesis.
2-Bromo-3-fluoro-6-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the fluorine atom facilitates target engagement through polar interactions. Its bench-stable nature and compatibility with standard synthetic workflows make it ideal for constructing complex heterocyclic scaffolds and API intermediates.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: