Piperidine-4-carbaldehydehydrochloride

Name: Piperidine-4-carbaldehydehydrochloride
Brand: ChemScene
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CAS No. 1159825-32-7
Cat. No. CS-0171609
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Piperidine-4-carbaldehydehydrochloride|CS-0171609

Structure of 1159825-32-7

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Description

Piperidine-4-carbaldehyde hydrochloride delivers a reactive aldehyde handle within a stable, bench-ready heterocyclic framework. This moisture-tolerant derivative integrates readily into synthetic sequences requiring electrophilic functionality at the C4 position of piperidine. The hydrochloride salt enhances solubility and handling in aqueous or polar organic media, streamlining use in medicinal chemistry and process development workflows.

Application

Piperidine-4-carbaldehyde hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to diverse heterocyclic scaffolds. Its aldehyde functionality facilitates reductive amination, Grignard additions, and condensation reactions under standard conditions. The hydrochloride salt enhances bench stability and simplifies handling, while maintaining compatibility with common protecting group strategies. This compound functions effectively in the synthesis of bioactive molecules requiring piperidine-based cores.

General Information

CAS No. 1159825-32-7
Cat. No. CS-0171609
Purity ≥95%
MDL No. None
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₁₂ClNO
Molecular Weight 149.62
Synonym(s) Piperidine-4-carbaldehyde hydrochloride
SMILES C1CNCCC1C=O.Cl

Computational Chemistry Data

TPSA 29.1
LogP 0.6067
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

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GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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Piperidine-4-carbaldehydehydrochloride

CAS No. 1159825-32-7

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