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Structure of 1160474-84-9
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4-Chloro-2-(dimethylamino)nicotinaldehyde features a strategically positioned chloro group and dimethylamino moiety on the nicotinaldehyde scaffold, enabling strong electron donation and enhanced reactivity in C–C coupling processes. This bench-stable aldehyde integrates readily into complex molecular architectures, particularly in the synthesis of bioactive heterocycles and fluorescent probes.
4-Chloro-2-(dimethylamino)nicotinaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through standard condensation and coupling reactions. Its electron-rich dimethylamino group enhances reactivity in nucleophilic additions, while the chloro substituent facilitates further functionalization via palladium-catalyzed cross-coupling. The aldehyde functionality allows for straightforward imine formation and reductive amination, supporting rapid diversification in target-oriented synthesis. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: