6-Bromo-5-methylimidazo[1,2-a]pyridine

Name: 6-Bromo-5-methylimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 116355-19-2
Cat. No. CS-0050260
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-5-methylimidazo[1,2-a]pyridine|CS-0050260

Structure of 116355-19-2

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Description

6-Bromo-5-methylimidazo[1,2-a]pyridine is a bench-stable heterocyclic building block featuring a bromine atom at the 6-position and a methyl group at the 5-position. This electronic configuration enables selective cross-coupling reactions and facilitates integration into pharmaceutical scaffolds and functional materials.

Application

6-Bromo-5-methylimidazo[1,2-a]pyridine serves as a versatile building block for heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined electrophilic bromide site. The methyl group enhances regiochemical control and provides metabolic stability in bioactive molecule design. This compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard coupling protocols, making it a practical choice for medicinal chemistry and process development workflows.

General Information

CAS No. 116355-19-2
Cat. No. CS-0050260
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrN₂
Molecular Weight 211.06
Synonym(s) IMidazo[1,2-a]pyridine, 6-broMo-5-Methyl-
SMILES CC1=C(Br)C=CC2=NC=CN12

Computational Chemistry Data

TPSA 17.3
LogP 2.40522
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-5-methylimidazo[1,2-a]pyridine

CAS No. 116355-19-2

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