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Structure of 13275-42-8
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2-(2-Bromophenyl)-1H-benzo[d]imidazole features a brominated phenyl moiety fused to a benzoimidazole core, delivering enhanced electron-withdrawing character and structural rigidity. This configuration supports efficient coupling in transition-metal-catalyzed reactions, enabling direct access to complex heterocyclic scaffolds under standard conditions.
2-(2-Bromophenyl)-1H-benzo[d]imidazole serves as a versatile building block for constructing biaryl- and heterocycle-containing scaffolds in medicinal chemistry. The bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating the synthesis of complex molecular architectures with high functional group tolerance and bench stability. Its rigid fused-ring structure supports predictable reactivity in standard coupling protocols, making it well-suited for late-stage functionalization and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P280-P302+P352-P330
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Lot numbers can be found on the outside label of a product: