Biotin-PEG5-azide

Name: Biotin-PEG5-azide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1163732-89-5
Cat. No. CS-0113102
Purity≥95%
MDL No.MFCD22683275

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 1163732-89-5

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Description

Biotin-PEG5-azide features a five-unit polyethylene glycol spacer linking biotin to a reactive azide group, enabling site-specific conjugation in bioconjugation workflows. This bifunctional reagent combines high-affinity biotin binding with efficient click chemistry compatibility, facilitating the labeling of proteins, nucleic acids, and other biomolecules under mild conditions.

Application

Biotin-PEG5-azide serves as a versatile bifunctional linker for bioconjugation, enabling site-specific labeling via strain-promoted or copper-catalyzed azide-alkyne cycloaddition. The PEG5 spacer provides enhanced solubility and reduced steric hindrance, while the azide group offers high reactivity with alkynes under mild conditions. This reagent facilitates efficient immobilization of biotinylated molecules on streptavidin-coated surfaces or affinity matrices, making it ideal for pull-down assays, protein conjugation, and targeted delivery systems.

General Information

CAS No. 1163732-89-5
Cat. No. CS-0113102
Purity ≥95%
MDL No. MFCD22683275
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₄₀N₆O₇S
Molecular Weight 532.65
Synonym(s) None
SMILES O=C(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O

Computational Chemistry Data

TPSA 165.14
LogP 1.2217
H_Acceptors 9
H_Donors 3
Rotatable_Bonds 23

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group PEG

Building Blocks Skeleton Aliphatic heterocycle compounds Imidazolidin compounds

Life Science Linker Biotin PEG

Life Science Linker PEG Azide

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Bioconjugation Biotins, Streptavidins

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Key Words

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Biotin-PEG5-azide

CAS No. 1163732-89-5

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