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Structure of 116632-14-5
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3-Iodonaphthalen-2-amine delivers a reactive iodine handle positioned ortho to a primary amine within a rigid naphthalene scaffold. This combination enables efficient coupling in cross-coupling protocols and facilitates conjugation to biomolecules or functional surfaces. The molecule exhibits stability under standard handling conditions and integrates readily into complex molecular architectures requiring site-specific attachment.
3-Iodonaphthalen-2-amine serves as a versatile building block in transition-metal-catalyzed coupling reactions, enabling efficient access to biaryl scaffolds. The iodine substituent facilitates reliable Suzuki, Stille, and Negishi couplings under standard conditions. The naphthalene core provides rigidity and π-conjugation beneficial for materials and pharmaceutical applications. Bench-stable and readily purified by chromatography, it functions effectively in multi-step synthesis workflows requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: