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Structure of 1166831-45-3
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Methyl 6-chloro-3-methylpyrazine-2-carboxylate features a pyrazine core with complementary electron-withdrawing and donor substituents, enabling efficient coupling in heterocyclic synthesis. The methyl ester group facilitates downstream derivatization, while the chlorine at the 6-position offers a handle for nucleophilic substitution under mild conditions. This compound serves as a key intermediate in medicinal chemistry and agrochemical development.
Methyl 6-chloro-3-methylpyrazine-2-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its pyrazine core supports palladium-catalyzed cross-coupling reactions, while the chloro and ester groups enable sequential functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns requiring orthogonality and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: