Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 6-chloro-3-methylpyrazine-2-carboxylate

  • CAS No. 1166831-45-3

  • Cat. No. CS-W022877
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 6-chloro-3-methylpyrazine-2-carboxylate|CS-W022877

Structure of 1166831-45-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1166831-45-3
  • Cat. No. CS-W022877
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇ClN₂O₂
  • Molecular Weight 186.60
  • Synonym(s) None
  • SMILES O=C(C1=NC(Cl)=CN=C1C)OC

Description

Methyl 6-chloro-3-methylpyrazine-2-carboxylate features a pyrazine core with complementary electron-withdrawing and donor substituents, enabling efficient coupling in heterocyclic synthesis. The methyl ester group facilitates downstream derivatization, while the chlorine at the 6-position offers a handle for nucleophilic substitution under mild conditions. This compound serves as a key intermediate in medicinal chemistry and agrochemical development.

Application

Methyl 6-chloro-3-methylpyrazine-2-carboxylate serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its pyrazine core supports palladium-catalyzed cross-coupling reactions, while the chloro and ester groups enable sequential functionalization. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns requiring orthogonality and predictable reactivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.08
  • LogP   1.22502
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1166831-45-3 sigma1166831-45-3 manufacturer1166831-45-3 price1166831-45-3 structure1166831-45-3 SDSbuy 1166831-45-31166831-45-3 supplier1166831-45-3 uses1166831-45-3 molecular weightprice of 1166831-45-31166831-45-3 chemical name formula of 1166831-45-3
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label