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Structure of 934180-48-0
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4-Chloro-2-methoxy-3-nitropyridine is a nitropyridine derivative featuring orthogonal reactivity at the chloro and nitro positions. This electron-deficient heterocycle integrates readily into cross-coupling cascades and serves as a key intermediate in the synthesis of bioactive pyridine-based scaffolds, offering predictable regioselectivity under standard conditions.
4-Chloro-2-methoxy-3-nitropyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloropyridine moiety. The methoxy and nitro groups provide orthogonal functional handles for sequential transformations, while the compound exhibits good bench stability and facilitates efficient purification. Its reactivity profile supports the synthesis of complex heterocyclic scaffolds commonly found in pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: