(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanylglycine

Name: (((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanylglycine
Brand: ChemScene
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CAS No. 116747-54-7
Cat. No. CS-0452330
Purity≥98%
MDL No.None

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(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanylglycine|CS-0452330

Structure of 116747-54-7

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Description

Fmoc-L-Ala-Gly is a protected dipeptide used in solid-phase peptide synthesis, featuring a fluorenylmethoxycarbonyl (Fmoc) group for orthogonal N-terminal protection. This derivative ensures efficient coupling and selective deprotection under mild basic conditions, enabling high-yielding assembly of complex peptide sequences with minimal side reactions.

Application

Fmoc-L-Ala-Gly serves as a reliable dipeptide building block for solid-phase peptide synthesis, offering excellent stability and ease of handling. The Fmoc group enables efficient orthogonal deprotection under mild basic conditions, while the L-alanyl-glycine sequence provides compatibility with standard coupling protocols. Its well-documented reactivity supports high-yielding peptide elongation and facilitates purification through crystallization or chromatography.

General Information

CAS No. 116747-54-7
Cat. No. CS-0452330
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₂₀N₂O₅
Molecular Weight 368.38
Synonym(s) N-[N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl]-glycine
SMILES C[C@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C(NCC(O)=O)=O

Computational Chemistry Data

TPSA 104.73
LogP 2.1144
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 6

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Amide

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Glycine and derivatives

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

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(((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanylglycine

CAS No. 116747-54-7

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