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CS-W001157 4
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6-Methylpyrazine-2-carbaldehyde

  • CAS No. 116758-01-1

  • Cat. No. CS-0054600
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Methylpyrazine-2-carbaldehyde|CS-0054600

Structure of 116758-01-1

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General Information

  • CAS No. 116758-01-1
  • Cat. No. CS-0054600
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O
  • Molecular Weight 122.12
  • Synonym(s) 6-Methylpyrazine-2-carboxaldehyde
  • SMILES O=CC1=NC(C)=CN=C1

Description

6-Methylpyrazine-2-carbaldehyde features a pyrazine core with methyl and formyl substituents positioned for enhanced electronic delocalization. This electron-deficient heterocycle serves as a key scaffold in flavor chemistry and medicinal intermediates, offering high reactivity at the aldehyde site. The compound exhibits bench-stable handling characteristics and integrates readily into complex molecular architectures.

Application

6-Methylpyrazine-2-carbaldehyde serves as a versatile heterocyclic building block in medicinal chemistry and flavor compound synthesis. Its pyrazine core provides metabolic stability, while the aldehyde functionality enables efficient derivatization via reductive amination, Schiff base formation, or nucleophilic addition. The methyl group enhances lipophilicity and offers a site for further functionalization. Bench-stable and compatible with standard synthetic protocols, it facilitates rapid access to diverse scaffolds in API development and agrochemical research.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   42.85
  • LogP   0.59752
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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