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Structure of 1168152-07-5
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Methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate features a conjugated enone system flanked by an acetyl group and a methoxy-substituted phenyl moiety, delivering enhanced stability and tunable reactivity. This indole scaffold integrates readily into complex heterocyclic architectures under mild conditions.
Methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate serves as a versatile dihydroindole scaffold for the synthesis of biologically relevant heterocycles. Its conjugated enone system enables reliable Michael additions and palladium-catalyzed coupling reactions. The methoxyphenylmethylene group provides orthogonal stability and facilitates selective deprotection, while the ester and acetyl functionalities support sequential functionalization. This compound exhibits excellent bench stability and is amenable to standard purification methods, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: