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CS-W001157 4
Total: USD 88.00

1-Boc-3-((Methylamino)methyl)azetidine

  • CAS No. 1049730-81-5

  • Cat. No. CS-0045524
  • Purity≥98%
  • MDL No.MFCD08061965
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Boc-3-((Methylamino)methyl)azetidine|CS-0045524

Structure of 1049730-81-5

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Description

1-Boc-3-((Methylamino)methyl)azetidine features a sterically hindered azetidine core with a methylamino-methyl side chain, enabling efficient incorporation into bioactive scaffolds. The Boc group provides stability during synthesis and facilitates selective deprotection under mild acidic conditions. This compound serves as a key building block for medicinal chemistry applications requiring nitrogen-rich heterocycles with tunable basicity and solubility.

Application

1-Boc-3-((methylamino)methyl)azetidine serves as a versatile building block for constructing nitrogen-containing heterocycles, particularly in medicinal chemistry and API development. The Boc-protected amine enables stable handling and selective deprotection under mild acidic conditions, while the pendant (methylamino)methyl group offers a reactive site for further functionalization. Its compatibility with standard coupling reactions and robust bench stability facilitate efficient synthesis of complex scaffolds.

General Information

  • CAS No. 1049730-81-5
  • Cat. No. CS-0045524
  • Purity ≥98%
  • MDL No. MFCD08061965
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₂
  • Molecular Weight 200.28
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CC(CNC)C1

Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.0727
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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