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Structure of 116855-08-4
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1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid is a heteroaromatic scaffold featuring a fused pyrazole-pyridine core with a carboxylic acid group at the 3-position. This configuration imparts enhanced solubility and directional reactivity, enabling direct incorporation into bioactive molecules and pharmaceutical intermediates. The acidic functionality facilitates salt formation and conjugation under mild conditions.
1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its rigid fused scaffold provides excellent metabolic stability and facilitates π-stacking interactions in target binding. The carboxylic acid group enables direct derivatization via amide coupling or esterification, while the pyrazolo[3,4-b]pyridine core exhibits favorable solubility and bench stability. This compound functions effectively in standard peptide coupling and transition-metal-catalyzed transformations, making it a practical choice for scaffold diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: