Thiazol-4-ylmethanamine hydrochloride

Name: Thiazol-4-ylmethanamine hydrochloride
Brand: ChemScene
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CAS No. 117043-86-4
Cat. No. CS-0038080
Purity≥96%
MDL No.MFCD06738774

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Thiazol-4-ylmethanamine hydrochloride|CS-0038080

Structure of 117043-86-4

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Description

Thiazol-4-ylmethanamine hydrochloride features a thiazole ring bearing a primary amine group at the 4-position, delivering a potent nucleophilic handle for conjugation. This bench-stable derivative integrates readily into bioconjugation workflows and serves as a key building block in medicinal chemistry, particularly for targeted drug delivery systems and kinase inhibitor scaffolds.

Application

Thiazol-4-ylmethanamine hydrochloride serves as a versatile building block for medicinal chemistry and catalytic synthesis. The thiazole scaffold provides robust metabolic stability and favorable pharmacokinetic properties, while the primary amine functionality enables straightforward derivatization via amide coupling, alkylation, or reductive amination. Its crystalline solid form ensures ease of handling and purification, with excellent bench stability under ambient conditions. This compound functions as a key intermediate in the construction of heterocyclic APIs and bioactive molecules.

General Information

CAS No. 117043-86-4
Cat. No. CS-0038080
Purity ≥96%
MDL No. MFCD06738774
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₇ClN₂S
Molecular Weight 150.63
Synonym(s) Thiazole-4-methylamine hydrochloride
SMILES NCC1=CSC=N1.Cl

Computational Chemistry Data

TPSA 38.91
LogP 1.0236
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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Thiazol-4-ylmethanamine hydrochloride

CAS No. 117043-86-4

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