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Structure of 1171891-35-2
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5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-ol features a boronate ester group conjugated to a pyridin-3-ol scaffold, enabling efficient Suzuki-Miyaura coupling under mild conditions. The tetramethyl-substituted dioxaborolane enhances stability and solubility in aqueous-organic mixtures, while the phenolic hydroxyl supports directional functionalization. This reagent streamlines the synthesis of biaryl heterocycles in medicinal chemistry and materials science.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-ol serves as a versatile boronate building block for Suzuki-Miyaura coupling, enabling efficient construction of biaryl scaffolds under mild conditions. The pyridin-3-ol functionality provides orthogonal reactivity and enhanced solubility, while the tetramethyl-substituted dioxaborolane offers excellent stability and ease of purification. This compound facilitates rapid access to functionalized heterocycles in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: