Fmoc-Gly-Phe-OH

Name: Fmoc-Gly-Phe-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 117370-45-3
Cat. No. CS-0343835
Purity≥98%
MDL No.MFCD00190882

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 117370-45-3

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Description

Fmoc-Gly-Phe-OH is a protected dipeptide intermediate featuring a fluorenylmethoxy carbonyl (Fmoc) group at the N-terminus and a phenylalanine side chain with free C-terminal carboxylic acid. This bench-stable, moisture-tolerant building block integrates seamlessly into solid-phase peptide synthesis workflows, enabling efficient coupling to extend peptide chains with high fidelity.

Application

Fmoc-Gly-Phe-OH serves as a key building block in solid-phase peptide synthesis, enabling efficient sequential coupling of amino acids. The Fmoc group provides orthogonal protection for the α-amino function, allowing selective deprotection under mild basic conditions. Glycine’s lack of a side chain enhances solubility and reduces steric hindrance during elongation, while the phenylalanine residue offers a hydrophobic handle useful in peptide folding studies and bioactive sequence design. The compound exhibits excellent bench stability and facilitates straightforward purification by flash chromatography or crystallization.

General Information

CAS No. 117370-45-3
Cat. No. CS-0343835
Purity ≥98%
MDL No. MFCD00190882
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₆H₂₄N₂O₅
Molecular Weight 444.48
Synonym(s) None
SMILES O=C([C@H](CC1=CC=CC=C1)NC(CNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)O

Computational Chemistry Data

TPSA 104.73
LogP 3.3372
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 8

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Fmoc

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

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Fmoc-Gly-Phe-OH

CAS No. 117370-45-3

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