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Structure of 1173897-86-3
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5-Bromo-6-methylpicolinonitrile features a sterically hindered pyridine core with complementary electron-withdrawing nitrile and bromo substituents. This configuration enables direct coupling in cross-coupling reactions, offering high functional group tolerance and stability under standard conditions.
5-Bromo-6-methylpicolinonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles via palladium-catalyzed cross-coupling reactions. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the nitrile and methyl functionalities offer orthogonal reactivity for downstream functionalization. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: