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CS-W001157 4
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(4-Bromo-3-Chlorophenyl)hydrazine hydrochloride

  • CAS No. 1177361-07-7

  • Cat. No. CS-0196533
  • Molecule weight257.94
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4-Bromo-3-Chlorophenyl)hydrazine hydrochloride|CS-0196533

Structure of 1177361-07-7

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General Information

  • CAS No. 1177361-07-7
  • Cat. No. CS-0196533
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrCl₂N₂
  • Molecular Weight 257.94
  • Synonym(s) 1-(4-BROMO-3-CHLOROPHENYL)HYDRAZINE, HCL
  • SMILES C1=CC(=C(C=C1NN)Cl)Br.Cl

Description

This bench-stable hydrazine derivative features a bromo-chloro-substituted phenyl core, enabling direct incorporation into heterocyclic scaffolds. The hydrochloride salt enhances solubility and handling, streamlining use in transition-metal-catalyzed couplings and the synthesis of bioactive triazoles and imidazoles under standard conditions.

Application

(4-Bromo-3-chlorophenyl)hydrazine hydrochloride serves as a key building block for constructing triazoles, pyrazoles, and other nitrogen-rich heterocycles via cyclization reactions. Its well-defined substitution pattern enables predictable regiochemistry in coupling processes, while the hydrazine moiety facilitates efficient metal-catalyzed transformations. The compound exhibits good bench stability and is compatible with standard purification techniques, making it a practical reagent for medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.8099
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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