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Structure of 117820-80-1
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3,5-Dichloro-4-fluorobenzaldehyde features a trifunctional aromatic core with electron-withdrawing halogens at the 3, 5-positions and a fluorine at the 4-position, enabling high reactivity in nucleophilic additions. The aldehyde group facilitates direct coupling reactions, while the ortho-halogens enhance stability under standard bench conditions. This scaffold integrates efficiently into complex heterocycles and pharmaceutical intermediates.
3,5-Dichloro-4-fluorobenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering predictable reactivity in nucleophilic additions, condensation reactions, and transition-metal-catalyzed couplings. Its electron-deficient aromatic ring enhances electrophilicity at the carbonyl center, enabling efficient formation of imines, hydrazones, and heterocycles. The molecule exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthetic workflows and modular scaffold development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: