tert-Butyl N-(2-azidoethyl)carbamate

Name: tert-Butyl N-(2-azidoethyl)carbamate
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CAS No. 117861-38-8
Cat. No. CS-0308109
Purity≥96%
MDL No.MFCD18207539

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tert-Butyl N-(2-azidoethyl)carbamate|CS-0308109

Structure of 117861-38-8

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Description

tert-Butyl N-(2-azidoethyl)carbamate is a bench-stable, moisture-tolerant azide reagent featuring a protected amine and a reactive terminal azide group. This bifunctional handle enables efficient copper-catalyzed or strain-promoted click chemistry for bioconjugation, polymer functionalization, and probe synthesis under standard conditions.

Application

tert-Butyl N-(2-azidoethyl)carbamate serves as a stable, bench-ready precursor for the introduction of azide-functionalized alkyl chains in synthetic workflows. It enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and functions as a protected amine handle in peptide and heterocycle synthesis. The tert-butyl carbamate group provides orthogonal protection with facile removal under mild acidic conditions, while the terminal azide supports diverse bioconjugation and click chemistry applications.

General Information

CAS No. 117861-38-8
Cat. No. CS-0308109
Purity ≥96%
MDL No. MFCD18207539
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₄N₄O₂
Molecular Weight 186.21
Synonym(s) N-Boc-2-azidoethylamine
SMILES CC(C)(OC(NCCN=[N+]=[N-])=O)C

Computational Chemistry Data

TPSA 87.09
LogP 1.8214
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Azide

Building Blocks Skeleton Fatty chain compounds

Life Science Click Chemistry Reagents Azide

Key Words

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tert-Butyl N-(2-azidoethyl)carbamate

CAS No. 117861-38-8

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