2,6-Dibromo-4-methoxypyridine

Name: 2,6-Dibromo-4-methoxypyridine
Brand: ChemScene
Availability: InStock
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CAS No. 117873-72-0
Cat. No. CS-W019246
Purity≥95%
MDL No.MFCD11036227

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2,6-Dibromo-4-methoxypyridine|CS-W019246

Structure of 117873-72-0

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Description

2,6-Dibromo-4-methoxypyridine features a pyridine core functionalized with bromine atoms at positions 2 and 6 and a methoxy group at C4, creating a sterically constrained, electron-deficient heterocycle. This configuration enables selective cross-coupling reactions in medicinal chemistry and materials synthesis, offering high reactivity under standard conditions with minimal side-product formation.

Application

2,6-Dibromo-4-methoxypyridine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine derivatives via palladium-catalyzed cross-coupling reactions. The ortho-bromine atoms facilitate sequential functionalization, while the methoxy group provides a handle for selective transformations. Its bench-stable crystalline form and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.

General Information

CAS No. 117873-72-0
Cat. No. CS-W019246
Purity ≥95%
MDL No. MFCD11036227
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅Br₂NO
Molecular Weight 266.92
Synonym(s) Pyridine,2,6-dibromo-4-methoxy
SMILES COC1=CC(Br)=NC(Br)=C1

Computational Chemistry Data

TPSA 22.12
LogP 2.6152
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,6-Dibromo-4-methoxypyridine

CAS No. 117873-72-0

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