2-Bromo-4-methoxypyridine

Name: 2-Bromo-4-methoxypyridine
Brand: ChemScene
Availability: InStock
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CAS No. 89488-29-9
Cat. No. CS-D1649
Purity≥96%
MDL No.MFCD06254613

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 89488-29-9

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Description

2-Bromo-4-methoxypyridine is a halogenated pyridine derivative featuring a bromine atom at the 2-position and a methoxy group at the 4-position. This combination imparts enhanced electrophilicity and regioselective reactivity in cross-coupling transformations. The molecule exhibits favorable stability under standard conditions, enabling reliable incorporation into diverse synthetic sequences.

Application

2-Bromo-4-methoxypyridine serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. Its bromine moiety enables reliable Suzuki, Stille, and Negishi coupling reactions, while the 4-methoxy group enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and is compatible with a range of functional groups, facilitating efficient construction of substituted pyridine scaffolds in API development.

General Information

CAS No. 89488-29-9
Cat. No. CS-D1649
Purity ≥96%
MDL No. MFCD06254613
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₆BrNO
Molecular Weight 188.02
Synonym(s) None
SMILES COC1=CC(Br)=NC=C1

Computational Chemistry Data

TPSA 22.12
LogP 1.8527
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromo-4-methoxypyridine

CAS No. 89488-29-9

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