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CS-W001157 4
Total: USD 88.00

2-(2-Chlorophenyl)cyclopropanecarboxylic acid

  • CAS No. 1181230-38-5

  • Cat. No. CS-0052303
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2-Chlorophenyl)cyclopropanecarboxylic acid|CS-0052303

Structure of 1181230-38-5

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General Information

  • CAS No. 1181230-38-5
  • Cat. No. CS-0052303
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉ClO₂
  • Molecular Weight 196.63
  • Synonym(s) None
  • SMILES OC(=O)C1CC1C1=C(Cl)C=CC=C1

Description

This cyclopropanecarboxylic acid derivative features a 2-chlorophenyl group attached to the cyclopropane ring, delivering enhanced lipophilicity and metabolic stability. The carboxylic acid moiety enables direct functionalization or salt formation. Designed for medicinal chemistry applications, it serves as a rigid bioisostere in target-oriented synthesis and drug discovery pipelines.

Application

2-(2-Chlorophenyl)cyclopropanecarboxylic acid serves as a valuable chiral building block in medicinal chemistry, enabling the construction of bioactive cyclopropyl-containing scaffolds. Its stability and defined stereochemistry facilitate downstream functionalization, while the ortho-chlorophenyl group offers favorable electronic and steric properties for coupling reactions and receptor interaction studies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.5281
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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