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Structure of 118289-07-9
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2,4,6-Trifluorbenzyl alcohol features a trifluoromethyl-substituted benzyl scaffold with enhanced electron-withdrawing character, enabling robust functionalization in cross-coupling and conjugation reactions. The hydroxyl group provides a handle for derivatization while maintaining stability under standard bench conditions.
2,4,6-Trifluorobenzyl alcohol serves as a versatile building block in medicinal chemistry, enabling efficient incorporation of trifluoromethylaryl motifs into target molecules. Its bench-stable nature and compatibility with diverse transformations—such as oxidation to the aldehyde, coupling reactions, and derivatization—facilitate rapid access to functionalized scaffolds. The electron-withdrawing trifluoromethyl groups enhance metabolic stability and modulate lipophilicity, making it particularly valuable for optimizing pharmacokinetic profiles in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: