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CS-W001157 4
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2,3,4,9-Tetrahydro-1h-carbazol-1-amine

  • CAS No. 118498-95-6

  • Cat. No. CS-0270355
  • Molecule weight186.25
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,3,4,9-Tetrahydro-1h-carbazol-1-amine|CS-0270355

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General Information

  • CAS No. 118498-95-6
  • Cat. No. CS-0270355
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₄N₂
  • Molecular Weight 186.25
  • Synonym(s) None
  • SMILES C1=CC=C2C(=C1)C3=C(C(CCC3)N)N2

Description

2,3,4,9-Tetrahydro-1H-carbazol-1-amine is a nitrogen-rich heterocycle featuring a saturated carbazole core with a primary amine at the 1-position. This bench-stable scaffold integrates readily into molecular architectures requiring electron-donating character and enhanced solubility in polar solvents.

Application

2,3,4,9-Tetrahydro-1H-carbazol-1-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard amine functionalization and coupling reactions. Its bench-stable, electron-rich core exhibits favorable reactivity in Suzuki-Miyaura and Buchwald-Hartwig couplings, facilitating access to complex molecular architectures with high functional group tolerance and predictable transformation profiles.

Safety Information

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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   41.81
  • LogP   2.504
  • H_Acceptors   1
  • H_Donors   2
  • Rotatable_Bonds   0

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