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6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride

  • CAS No. 1187830-46-1

  • Cat. No. CS-0038833
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride|CS-0038833

Structure of 1187830-46-1

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General Information

  • CAS No. 1187830-46-1
  • Cat. No. CS-0038833
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈ClN₃
  • Molecular Weight 157.60
  • Synonym(s) None
  • SMILES [H]Cl.C12=NC=NC=C1CNC2

Description

6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride is a bench-stable heterocyclic scaffold featuring a saturated pyrrole ring fused to a dihydropyrimidine core. This nitrogen-rich system serves as a key building block in medicinal chemistry, offering favorable solubility and reactivity for incorporation into bioactive molecules.

Application

6,7-Dihydro-5H-pyrrolo[3,4-d]pyrimidine hydrochloride serves as a valuable heterocyclic building block in medicinal chemistry, enabling efficient access to purine-like scaffolds. Its well-defined reactivity facilitates functionalization at multiple positions, supporting diverse coupling and substitution reactions. The hydrochloride salt enhances bench stability and solubility, simplifying handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501

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Computational Chemistry Data

  • TPSA   37.81
  • LogP   0.5016
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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