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CS-W001157 4
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3-Amino-6-bromopyridin-2(1H)-one hydrobromide

  • CAS No. 1187930-34-2

  • Cat. No. CS-W021841
  • Purity≥97%
  • MDL No.MFCD09701347

*For research and further manufacturing use only, not for direct human use.

3-Amino-6-bromopyridin-2(1H)-one hydrobromide|CS-W021841

Structure of 1187930-34-2

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General Information

  • CAS No. 1187930-34-2
  • Cat. No. CS-W021841
  • Purity ≥97%
  • MDL No. MFCD09701347
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆Br₂N₂O
  • Molecular Weight 269.92
  • Synonym(s) 3-amino-6-bromo-pyridin-2-ol hydrobromide
  • SMILES O=C1C(N)=CC=C(Br)N1.[H]Br

Description

3-Amino-6-bromopyridin-2(1H)-one hydrobromide delivers a brominated pyridinone scaffold with enhanced solubility and stability under standard conditions. The amino and bromo substituents enable efficient coupling reactions, while the hydrobromide salt ensures reliable handling and incorporation into synthetic sequences.

Application

3-Amino-6-bromopyridin-2(1H)-one hydrobromide serves as a versatile building block in medicinal chemistry, enabling efficient access to brominated pyridone scaffolds. The compound exhibits robust bench stability and facilitates direct functionalization at the amino and bromo positions, supporting coupling reactions and heterocycle elaboration. Its compatibility with palladium-catalyzed transformations and orthogonality in multi-step syntheses makes it a practical choice for API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   58.88
  • LogP   1.2975
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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