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Structure of 1189169-37-6
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1-(5-Bromopyrimidin-2-yl)ethanone features a brominated pyrimidine core paired with an acetyl group, enabling direct integration into heterocyclic scaffolds. This electron-deficient building block facilitates cross-coupling reactions and serves as a key intermediate in medicinal chemistry for targeted functionalization.
1-(5-Bromopyrimidin-2-yl)ethanone serves as a versatile building block in synthetic medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. The bromine atom at the 5-position facilitates palladium-catalyzed cross-coupling reactions, while the acetyl group provides a handle for further functionalization via enolization or nucleophilic substitution. Its bench stability and compatibility with standard reaction conditions make it a practical choice for modular synthesis of bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: