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Structure of 119022-51-4
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1-Methyl-5-trifluoromethyl-1,2-dihydropyrazol-3-one features a trifluoromethyl group that imparts enhanced electron-withdrawing character and metabolic stability. This dihydropyrazolone scaffold integrates readily into medicinal chemistry campaigns, offering a rigid, polarized framework for targeted molecular design.
1-Methyl-5-trifluoromethyl-1,2-dihydropyrazol-3-one serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized pyrazole scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the enolizable carbonyl supports diverse transformations including nucleophilic additions and coupling reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: