8-Bromo-2-methylimidazo[1,2-a]pyridine

Name: 8-Bromo-2-methylimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 1194374-75-8
Cat. No. CS-0239063
Purity≥98%
MDL No.None

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Excepted Quantity	$0.00
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8-Bromo-2-methylimidazo[1,2-a]pyridine|CS-0239063

Structure of 1194374-75-8

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Description

8-Bromo-2-methylimidazo[1,2-a]pyridine features a fused heterocyclic core combining imidazo[1,2-a]pyridine with bromo and methyl substituents at the 8- and 2-positions, respectively. This electron-deficient scaffold enables direct functionalization in cross-coupling reactions and serves as a key building block in medicinal chemistry for kinase inhibitors and bioactive scaffolds.

Application

8-Bromo-2-methylimidazo[1,2-a]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of imidazo[1,2-a]pyridine scaffolds via palladium-catalyzed cross-coupling reactions. Its bromine at the C8 position provides a reliable site for further functionalization, while the methyl group enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with standard synthetic protocols, facilitating scalable synthesis of potential kinase inhibitors and other bioactive molecules.

General Information

CAS No. 1194374-75-8
Cat. No. CS-0239063
Purity ≥98%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrN₂
Molecular Weight 211.06
Synonym(s) None
SMILES CC1=CN2C=CC=C(C2=N1)Br

Computational Chemistry Data

TPSA 17.3
LogP 2.40522
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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8-Bromo-2-methylimidazo[1,2-a]pyridine

CAS No. 1194374-75-8

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