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Structure of 1196153-95-3
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Ethyl 7-bromoquinoline-2-carboxylate features a brominated quinoline core with an ester-functionalized C2 position, enabling direct coupling in cross-coupling reactions. The electron-deficient aromatic system enhances reactivity in palladium-catalyzed transformations, while the ethyl ester group offers tunable polarity and stability under standard bench conditions. This compound serves as a modular scaffold for synthesizing bioactive heterocycles and advanced pharmaceutical intermediates.
Ethyl 7-bromoquinoline-2-carboxylate serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions at the C7 position. The quinoline scaffold provides structural rigidity and favorable pharmacophoric properties, while the bromine atom offers high reactivity in Suzuki, Stille, and Negishi couplings. The ester group allows for further derivatization, and the compound exhibits good bench stability and ease of purification, making it well-suited for modular synthesis of complex heterocyclic systems and potential API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: