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Structure of 20776-52-7
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2-Amino-6-iodobenzoic acid features a carboxylic acid group flanked by an amino substituent and a bulky iodine atom at the para-position relative to the amine. This combination imparts strong electron-donating character and enhanced steric profile, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. The molecule demonstrates excellent bench stability and solubility in polar organic solvents, facilitating straightforward integration into synthetic workflows for bioconjugation and pharmaceutical intermediate development.
2-Amino-6-iodobenzoic acid serves as a versatile building block for constructing biologically relevant heterocycles and pharmaceutical intermediates. Its ortho-amino and iodine functionalities enable sequential cross-coupling and cyclization reactions, facilitating efficient access to complex scaffolds. The compound exhibits good bench stability and compatibility with standard purification methods, making it suitable for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335-H312-H332
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: