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Structure of 1197-10-0
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6-(Hydroxymethyl)picolinic acid features a pyridine ring bearing both carboxylic acid and hydroxymethyl functional groups at adjacent positions, enabling versatile conjugation and coordination chemistry. This bifunctional scaffold integrates readily into bioconjugates, metal chelators, and polymer architectures under standard conditions. The pendant hydroxyl group enhances solubility and provides a handle for derivatization, while the acidic proton facilitates salt formation and pH-responsive behavior.
6-(Hydroxymethyl)picolinic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its ortho-carboxylic acid and hydroxymethyl groups enable sequential functionalization, including oxidation to aldehyde or carboxylic acid, esterification, and coupling reactions. The molecule exhibits good bench stability and facilitates purification via standard chromatographic or crystallization methods, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: