(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid
Brand: ChemScene
Availability: InStock
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CAS No. 1197020-22-6
Cat. No. CS-0120226
Purity≥97%
MDL No.MFCD08275892

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid|CS-0120226

Structure of 1197020-22-6

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Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid is a chiral, bench-stable amino acid derivative featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group. This robust, moisture-tolerant building block integrates seamlessly into peptide synthesis workflows, enabling efficient N-terminal protection and selective coupling in solid-phase and solution-phase strategies.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid serves as a valuable chiral building block in peptide synthesis, offering high stereoselectivity and bench stability. The Fmoc group enables orthogonal protection of the amine, facilitating efficient coupling reactions under standard conditions. Its aliphatic side chain provides structural diversity for peptidomimetic design, while the carboxylic acid functionality supports direct conjugation or further derivatization in modular synthetic sequences.

General Information

CAS No. 1197020-22-6
Cat. No. CS-0120226
Purity ≥97%
MDL No. MFCD08275892
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₅NO₄
Molecular Weight 367.44
Synonym(s) N-Fmoc-(S)-2-pentylglycine
SMILES O=C(O)[C@H](CCCCC)NC(OCC1C2=CC=CC=C2C3=CC=CC=C13)=O

Computational Chemistry Data

TPSA 75.63
LogP 4.5586
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 8

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Leucine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)heptanoic acid

CAS No. 1197020-22-6

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