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Structure of 1197953-47-1
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(2-Aminophenyl)dimethylphosphine oxide features a phosphine oxide moiety tethered to an ortho-aminophenyl group, delivering a sterically accessible coordination site. This bench-stable ligand integrates readily into palladium-catalyzed cross-coupling systems, enabling efficient bond formation under mild conditions.
(2-Aminophenyl)dimethylphosphine oxide serves as a versatile ligand in transition metal catalysis, particularly in palladium-catalyzed cross-coupling reactions. Its ortho-amino group enables chelation to metals, enhancing catalyst stability and reactivity. The dimethylphosphine oxide moiety offers good bench stability, mild handling, and tolerance to various functional groups, facilitating efficient synthesis of biaryl and heterocyclic scaffolds common in medicinal chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: