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Structure of 1198103-43-3
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This difluoromethoxy-substituted pyridyl methylamine features a bench-stable, electron-deficient heteroaryl scaffold that integrates readily into medicinal chemistry libraries. The para-difluoromethoxy group enhances metabolic stability and modulates lipophilicity, while the primary amine enables straightforward conjugation for probe development.
(6-(Difluoromethoxy)pyridin-3-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amine coupling and electrophilic substitution reactions. Its difluoromethoxy group enhances metabolic stability and modulates lipophilicity, while the primary amine facilitates conjugation with carboxylic acids, isocyanates, and aldehydes. The compound exhibits good bench stability and ease of purification, making it well-suited for high-throughput synthesis and API development workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314-H318
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: