6-Bromooxazolo[5,4-b]pyridin-2-amine

Name: 6-Bromooxazolo[5,4-b]pyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1198319-39-9
Cat. No. CS-0157360
Purity≥95%
MDL No.MFCD16658714

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromooxazolo[5,4-b]pyridin-2-amine|CS-0157360

Structure of 1198319-39-9

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Description

6-Bromooxazolo[5,4-b]pyridin-2-amine features a brominated oxazolopyridine core with a strategically positioned amine group, enabling direct coupling in cross-coupling reactions. This scaffold combines electronic tunability with robust stability under standard conditions, facilitating rapid integration into complex heterocyclic architectures for medicinal chemistry and materials applications.

Application

6-Bromooxazolo[5,4-b]pyridin-2-amine serves as a versatile building block for constructing bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions with high efficiency. The bromine at the 6-position facilitates reliable functionalization, while the oxazolopyridine core provides excellent stability and compatibility with diverse reaction conditions. This compound functions effectively in the synthesis of pharmaceutical scaffolds and advanced intermediates, offering predictable reactivity and straightforward purification.

General Information

CAS No. 1198319-39-9
Cat. No. CS-0157360
Purity ≥95%
MDL No. MFCD16658714
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄BrN₃O
Molecular Weight 214.02
Synonym(s) 6-Bromo-oxazolo[5,4-b]pyridin-2-ylamine
SMILES NC1=NC2=CC(Br)=CN=C2O1

Computational Chemistry Data

TPSA 64.94
LogP 1.5675
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Oxazole compounds

Key Words

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6-Bromooxazolo[5,4-b]pyridin-2-amine

CAS No. 1198319-39-9

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