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Structure of 1201924-32-4
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6-Chloro-3-methylpicolinic acid features a sterically hindered pyridine core with complementary electron-withdrawing and donating substituents. This combination enhances its utility as a building block in medicinal chemistry, enabling efficient coupling reactions under mild conditions. The chloro group facilitates downstream functionalization, while the methyl moiety imparts increased lipophilicity and metabolic stability.
6-Chloro-3-methylpicolinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-chloro and methyl substituents enable selective functionalization, while the carboxylic acid group facilitates coupling reactions. The compound exhibits good bench stability and is compatible with standard amide bond formation, Suzuki-Miyaura cross-coupling, and cyclization protocols used in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: