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CS-W001157 4
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Methyl 4,6-dibromopicolinate

  • CAS No. 1206248-47-6

  • Cat. No. CS-0146038
  • Purity≥95%
  • MDL No.MFCD14582014

*For research and further manufacturing use only, not for direct human use.

Methyl 4,6-dibromopicolinate|CS-0146038

Structure of 1206248-47-6

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General Information

  • CAS No. 1206248-47-6
  • Cat. No. CS-0146038
  • Purity ≥95%
  • MDL No. MFCD14582014
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅Br₂NO₂
  • Molecular Weight 294.93
  • Synonym(s) 2-Pyridinecarboxylic acid,4,6-dibromo-,methyl ester
  • SMILES O=C(C1=NC(Br)=CC(Br)=C1)OC

Description

Methyl 4,6-dibromopicolinate features two bromine atoms at the 4- and 6-positions of the picolinate ring, creating a highly electron-deficient heterocyclic scaffold. This structural motif enables direct functionalization in cross-coupling reactions and serves as a key building block for brominated pyridine derivatives used in medicinal chemistry and agrochemical development.

Application

Methyl 4,6-dibromopicolinate serves as a versatile building block for the synthesis of brominated heterocycles and pharmaceutical intermediates. Its dual bromine substituents at the 4- and 6-positions enable sequential cross-coupling reactions, facilitating the construction of complex aryl scaffolds. The ester functionality offers compatibility with standard transformations, while the molecule exhibits good bench stability and ease of purification, making it well-suited for iterative synthetic workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   2.3932
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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