2,4-Dibromo-5-methylthiazole

Name: 2,4-Dibromo-5-methylthiazole
Brand: ChemScene
Availability: InStock
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CAS No. 1206708-88-4
Cat. No. CS-W005752
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 1206708-88-4

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Description

2,4-Dibromo-5-methylthiazole features a sterically accessible thiazole core with two bromine substituents at electron-deficient positions and a methyl group at C5, enabling direct functionalization in cross-coupling reactions. This bench-stable heterocycle integrates readily into bioactive scaffolds and materials architectures requiring halogenated building blocks.

Application

2,4-Dibromo-5-methylthiazole serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiazole scaffolds via palladium-catalyzed cross-coupling reactions. The bromine atoms at the 2- and 4-positions offer orthogonal reactivity for sequential functionalization, while the methyl group enhances stability and modulates electronic properties. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for medicinal chemistry campaigns and process-scale applications.

General Information

CAS No. 1206708-88-4
Cat. No. CS-W005752
Purity ≥98%
MDL No. None
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₃Br₂NS
Molecular Weight 256.95
Synonym(s) None
SMILES CC1=C(Br)N=C(Br)S1

Computational Chemistry Data

TPSA 12.89
LogP 2.97652
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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2,4-Dibromo-5-methylthiazole

CAS No. 1206708-88-4

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