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CS-W001157 4
Total: USD 88.00

4-Borono-3-fluorobenzoic acid

  • CAS No. 851335-07-4

  • Cat. No. CS-W017029
  • Purity≥97%
  • MDL No.MFCD08458473
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Borono-3-fluorobenzoic acid|CS-W017029

Structure of 851335-07-4

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Description

4-Borono-3-fluorobenzoic acid features a strategically positioned boronate group paired with a fluorine substituent and carboxylic acid functionality. This combination enables selective bioorthogonal labeling in complex biological environments while maintaining stability under standard handling conditions. The electron-deficient aryl ring enhances reactivity in Suzuki-Miyaura coupling, facilitating efficient integration into diverse molecular architectures.

Application

4-Borono-3-fluorobenzoic acid serves as a versatile building block for the synthesis of boron-containing heterocycles and bioactive molecules. Its ortho-fluoro and boronic acid functionalities enable efficient Suzuki-Miyaura cross-coupling and facilitate directed metalation, offering high chemoselectivity and stability under standard reaction conditions. The carboxylic acid group provides a handle for derivatization and conjugation, enhancing its utility in medicinal chemistry and materials science applications.

General Information

  • CAS No. 851335-07-4
  • Cat. No. CS-W017029
  • Purity ≥97%
  • MDL No. MFCD08458473
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BFO₄
  • Molecular Weight 183.93
  • Synonym(s) Benzoic acid,4-borono-3-fluoro-
  • SMILES OB(O)C1=C(F)C=C(C=C1)C(O)=O

Computational Chemistry Data

  • TPSA   77.76
  • LogP   -0.7963
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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