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CS-W001157 4
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tert-Butyl 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

  • CAS No. 1207175-15-2

  • Cat. No. CS-0214922
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate|CS-0214922

Structure of 1207175-15-2

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General Information

  • CAS No. 1207175-15-2
  • Cat. No. CS-0214922
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₂N₂O₂
  • Molecular Weight 262.35
  • Synonym(s) (R)-tert-butyl 1-(aminomethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
  • SMILES C=1C=CC2=C(C1)CCN(C2CN)C(=O)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      1118640-91-7
    • ~81%
    • tert-Butyl 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate|CS-0214922
      1207175-15-2

    References

    • Sadhu, Partha Sarathi; Kumar, Singam Naveen; Chandrasekharam, Malapaka; Pica-Mattoccia, Livia; Cioli, Donato; Rao, Vaidya Jayathirtha Bioorganic and Medicinal Chemistry Letters, 2012 ,  vol. 22,  # 2  p. 1103 - 1106
  • Route2
    • 2-(3,4-Dihydroisoquinolin-1-ylmethyl)isoindole-1,3-dione|CS-0036860
      88422-83-7
    • ~%
    • tert-Butyl 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate|CS-0214922
      1207175-15-2

    References

    • RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; THE BROAD INSTITUTE, INC.; HU, Longqin; MAGESH, Sadagopan; CHEN, Lin; LEWIS, Timothy; MUNOZ, Ben; WANG, Lili Patent:   WO2013/67036 A1, 2013 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   2.4796
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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