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Structure of 1209459-16-4
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2-Bromopyrimidine-4-carbonitrile features a bromine atom at the 2-position and a nitrile group at the 4-position on a pyrimidine scaffold, delivering a potent electrophilic handle for nucleophilic substitution. This dual functionality enables efficient coupling in cross-coupling reactions and facilitates the synthesis of complex heterocyclic architectures. The molecule exhibits enhanced reactivity due to the electron-withdrawing nature of both substituents, allowing for selective functionalization under mild conditions. Its bench-stable form simplifies handling in synthetic workflows.
2-Bromopyrimidine-4-carbonitrile serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive bromine and electron-deficient pyrimidine core. The nitrile group provides additional handle for functionalization, while the molecule exhibits bench stability and compatibility with standard purification methods. It functions effectively in the construction of bioactive scaffolds and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: