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Structure of 1209460-14-9
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4-Bromo-2-cyclopropoxypyridine features a cyclopropoxy group at the 2-position and a bromine atom at the 4-position of the pyridine ring, enabling efficient coupling in cross-coupling reactions. The sterically constrained cyclopropyl moiety enhances stability and modulates electronic properties, making this scaffold valuable for medicinal chemistry and materials synthesis under standard conditions.
4-Bromo-2-cyclopropoxypyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to install aryl and heteroaryl extensions. The bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the cyclopropoxy group offers metabolic stability and favorable lipophilicity. Its bench-stable solid form facilitates handling and purification, making it suitable for iterative synthesis of bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: