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Structure of 120984-76-1
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2-Bromo-3-methylpyrazine is a halogenated heterocyclic compound featuring a pyrazine core with strategically positioned bromo and methyl substituents. This configuration enables direct functionalization in cross-coupling reactions, offering a reliable entry point for synthesizing bioactive analogs and advanced pharmaceutical intermediates under standard conditions.
2-Bromo-3-methylpyrazine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions to construct biaryl and alkylated pyrazine derivatives. The bromine substituent provides high reactivity in Suzuki, Stille, and Negishi couplings, while the methyl group enhances solubility and modulates electronic properties. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: